Lazar Mandinov, M.D., Ph.D.

Lazar joined Parexel International Corporation in April 2014 and has more than 16 years of experience in the biotech and medical device industries. He is an expert in clinical development (Phase I-IV trials), medical affairs, safety, and clinical/regulatory affairs, including multiple interactions with FDA, notified bodies in Europe, and other regulatory agencies. His responsibilities include providing scientific and strategic guidance to customers and internal project groups with an emphasis on medical issues, medical monitoring, consulting in clinical drug development from pre-clinical through post marketing, support for protocol development, regulatory submissions and manuscript development, therapeutic area training, evaluation of new technologies and safety monitoring.

Work experience

Lazar has extensive expertise in coronary and structural heart interventions, heart failure, heart transplantation, hypertension, angiogenesis, coronary restenosis and stent thrombosis, cell biology, inflammation, and animal disease models. He is board-certified in internal medicine and cardiology. Lazar previously served as chief medical officer and vice president clinical at Mitralign in Tewksbury, MA, and medical director at Boston Scientific in Natick, MA. Prior to that, he spent two years at the Maine Medical Research Institute in Scarborough, ME where he headed several research projects involving the development of novel therapies for coronary restenosis and atherosclerosis. Lazar worked as an interventional cardiologist at the National Center for Cardiovascular Disease in Sofia for two years, when he was also assistant professor of cardiology, and the University Hospital Zurich and the University Hospital Bern, Switzerland for six years.

Lazar has published more than 100 manuscripts, book chapters, and abstracts and was a recipient of research grants, and a winner of international and national awards.

Education

Lazar completed his internal medicine training at the Medical University in Sofia, Bulgaria at the same time when he was attending the M.D., Ph.D. program. Lazar completed cardiology fellowship training at National Center for Cardiovascular Disease in Sofia, Bulgaria with a concentration in interventional cardiology.